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Microglia Express CCR5, CXCR4, and CCR3, but of These, CCR5 Is the Principal Coreceptor for Human Immunodeficiency Virus Type 1 Dementia Isolates

Microglia are the main human immunodeficiency virus (HIV) reservoir in the central nervous system and most likely play a major role in the development of HIV dementia (HIVD). To characterize human adult microglial chemokine receptors, we analyzed the expression and calcium signaling of CCR5, CCR3, a...

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Udgivet i:J Virol
Principais autores: Albright, Andrew V., Shieh, Joseph T. C., Itoh, Takayuki, Lee, Benhur, Pleasure, David, O’Connor, Michael J., Doms, Robert W., González-Scarano, Francisco
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103824/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9847323/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.1.205-213.1999
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