Role of Interferon Regulatory Factor 7 in T Cell Responses during Acute Lymphocytic Choriomeningitis Virus Infection

Type I interferons (IFNs), predominantly IFN-α and -β, play critical roles in both innate and adaptive immune responses against viral infections. Interferon regulatory factor 7 (IRF7), a key innate immune molecule in the type I IFN signaling pathway, is essential for the type I IFN response to many...

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Detalhes bibliográficos
Main Authors: Zhou, Shenghua, Cerny, Anna M., Fitzgerald, Katherine A., Kurt-Jones, Evelyn A., Finberg, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457134/
https://ncbi.nlm.nih.gov/pubmed/22875973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00576-12
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