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Induction and Inhibition of Type I Interferon Responses by Distinct Components of Lymphocytic Choriomeningitis Virus

Type I interferons (IFNs) play a critical role in the host defense against viruses. Lymphocytic choriomeningitis virus (LCMV) infection induces robust type I IFN production in its natural host, the mouse. However, the mechanisms underlying the induction of type I IFNs in response to LCMV infection h...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhou, Shenghua, Cerny, Anna M., Zacharia, An, Fitzgerald, Katherine A., Kurt-Jones, Evelyn A., Finberg, Robert W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937596/
https://ncbi.nlm.nih.gov/pubmed/20592086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00155-10
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