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Type 1 Interferon Induction of Natural Killer Cell Gamma Interferon Production for Defense during Lymphocytic Choriomeningitis Virus Infection

Natural killer (NK) cells are equipped to innately produce the cytokine gamma interferon (IFN-γ) in part because they basally express high levels of the signal transducer and activator of transcription 4 (STAT4). Type 1 interferons (IFNs) have the potential to activate STAT4 and promote IFN-γ expres...

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Detalhes bibliográficos
Main Authors: Mack, Ethan A., Kallal, Lara E., Demers, Delia A., Biron, Christine A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150756/
https://ncbi.nlm.nih.gov/pubmed/21828218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00169-11
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