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Identification of Amino Acid Residues Critical for the Anti-Interferon Activity of the Nucleoprotein of the Prototypic Arenavirus Lymphocytic Choriomeningitis Virus

Lymphocytic choriomeningitis virus (LCVM) nucleoprotein (NP) counteracts the host type I interferon (IFN) response by inhibiting activation of the IFN regulatory factor 3 (IRF3). In this study, we have mapped the regions and specific amino acid residues within NP involved in its anti-IFN activity. W...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Martínez-Sobrido, Luis, Emonet, Sébastien, Giannakas, Panagiotis, Cubitt, Beatrice, García-Sastre, Adolfo, de la Torre, Juan C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772779/
https://ncbi.nlm.nih.gov/pubmed/19710144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00763-09
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