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MDA5 and MAVS Mediate Type I Interferon Responses to Coxsackie B Virus
Coxsackie B viruses (CVB) are enteroviruses that have been associated with a variety of human diseases, including myocarditis. In the present study, we found that MDA5 and its adaptor molecule MAVS are critical for type I interferon responses to CVB, since the absence of either MAVS or MDA5 leads to...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2798442/ https://ncbi.nlm.nih.gov/pubmed/19846534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00631-09 |
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