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Importance of β-Catenin in glucose and energy homeostasis

In settings of increased insulin demand, failure to expand pancreatic β-cells mass leads to diabetes. Genome-wide scans of diabetic populations have uncovered several genes associated with susceptibility to type 2 diabetes and a number of them are part of the Wnt signaling. β-Catenin, a Wnt downstre...

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Autors principals: Elghazi, Lynda, Gould, Aaron P., Weiss, Aaron J., Barker, Daniel J., Callaghan, John, Opland, Darren, Myers, Martin, Cras-Méneur, Corentin, Bernal-Mizrachi, Ernesto
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457035/
https://ncbi.nlm.nih.gov/pubmed/23012647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00693
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