Human NKG2D-ligands: cell biology strategies to ensure immune recognition

Immune recognition mediated by the activating receptor NKG2D plays an important role for the elimination of stressed cells, including tumors and virus-infected cells. On the other hand, the ligands for NKG2D can also be shed into the sera of cancer patients where they weaken the immune response by d...

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Bibliographic Details
Main Authors: Fernández-Messina, Lola, Reyburn, Hugh T., Valés-Gómez, Mar
Format: Artigo
Language:Inglês
Published: Frontiers Research Foundation 2012
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457034/
https://ncbi.nlm.nih.gov/pubmed/23056001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00299
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