Palmitoylation of MICA, a ligand for NKG2D, mediates its recruitment to membrane microdomains and promotes its shedding

MICA and MICB (MHC-class-I-related chain A/B) are transmembrane proteins expressed in pathological conditions that are ligands for NKG2D, an activating receptor found on cytotoxic lymphocytes. The recognition on target cells of NKG2D ligands leads to the activation of lysis and cytokine secretion by...

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Bibliografiset tiedot
Päätekijät: Agüera-González, Sonia, Gross, Catharina C., Fernández-Messina, Lola, Ashiru, Omodele, Esteso, Gloria, Hang, Howard C., Reyburn, Hugh T., Long, Eric O., Valés-Gómez, Mar
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3709245/
https://ncbi.nlm.nih.gov/pubmed/21928280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201141645
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