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The human NKG2D ligand ULBP2 can be expressed at the cell surface with or without a GPI anchor and both forms can activate NK cells

The activating immune receptor NKG2D binds to several stress-induced ligands that are structurally different. MHC-class-I-related chain (MIC) A/B molecules have a transmembrane domain, whereas most UL16 binding proteins (ULBPs) are glycosylphosphatidylinositol (GPI)-linked molecules. The significanc...

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書誌詳細
主要な著者: Fernández-Messina, Lola, Ashiru, Omodele, Agüera-González, Sonia, Reyburn, Hugh T., Valés-Gómez, Mar
フォーマット: Artigo
言語:Inglês
出版事項: Company of Biologists 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021996/
https://ncbi.nlm.nih.gov/pubmed/21224393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.076042
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