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Differential Mechanisms of Shedding of the Glycosylphosphatidylinositol (GPI)-anchored NKG2D Ligands

Tumor cells release NKG2D ligands to evade NKG2D-mediated immune surveillance. The purpose of our investigation was to explore the cellular mechanisms of release used by various members of the ULBP family. Using biochemical and cellular approaches in both transfectant systems and tumor cell lines, t...

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Main Authors: Fernández-Messina, Lola, Ashiru, Omodele, Boutet, Philippe, Agüera-González, Sonia, Skepper, Jeremy N., Reyburn, Hugh T., Valés-Gómez, Mar
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838276/
https://ncbi.nlm.nih.gov/pubmed/20080967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.045906
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