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Short Communication: Rapid Detection of the ΔF508 Mutation in Single Cells Using DHPLC: Implications for Preimplantation Genetic Diagnosis
Purpose: Practice of preimplantation genetic diagnosis (PGD) requires efficient amplification and analysis techniques. We have tested Denaturing High Performance Liquid Chromatography (DHPLC) to screen the Δ F508 mutation in heterozygous single cells in order to assess its usefulness for PGD of cyst...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Kluwer Academic Publishers-Plenum Publishers
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3455635/ https://ncbi.nlm.nih.gov/pubmed/12762414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1022981103862 |
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