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Short Communication: Rapid Detection of the ΔF508 Mutation in Single Cells Using DHPLC: Implications for Preimplantation Genetic Diagnosis

Purpose: Practice of preimplantation genetic diagnosis (PGD) requires efficient amplification and analysis techniques. We have tested Denaturing High Performance Liquid Chromatography (DHPLC) to screen the Δ F508 mutation in heterozygous single cells in order to assess its usefulness for PGD of cyst...

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Detalhes bibliográficos
Main Authors: Girardet, Anne, Cathala, Philippe, Claustres, Mireille
Formato: Artigo
Idioma:Inglês
Publicado em: Kluwer Academic Publishers-Plenum Publishers 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3455635/
https://ncbi.nlm.nih.gov/pubmed/12762414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1022981103862
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