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Long-lived Ames dwarf mice: Oxidative damage to mitochondrial DNA in heart and brain

The single gene mutation of Ames dwarf mice increases their maximum longevity by around 40% but the mechanism(s) responsible for this effect remain to be identified. This animal model thus offers a unique possibility of testing the mitochondrial theory of aging. In this investigation, oxidative dama...

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Detaylı Bibliyografya
Asıl Yazarlar: Sanz, Alberto, Bartke, Andrzej, Barja, Gustavo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Kluwer Academic Publishers 2002
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3455243/
https://ncbi.nlm.nih.gov/pubmed/23604907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-002-0010-3
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