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Long-lived Ames dwarf mice: Oxidative damage to mitochondrial DNA in heart and brain
The single gene mutation of Ames dwarf mice increases their maximum longevity by around 40% but the mechanism(s) responsible for this effect remain to be identified. This animal model thus offers a unique possibility of testing the mitochondrial theory of aging. In this investigation, oxidative dama...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Kluwer Academic Publishers
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3455243/ https://ncbi.nlm.nih.gov/pubmed/23604907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-002-0010-3 |
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