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Probing Ion Channel Activity of Human Islet Amyloid Polypeptide (Amylin)

Interactions of human islet amyloid polypeptide (hIAPP or amylin) with the cell membrane are correlated with the dysfunction and death of pancreatic islet β-cells in type II diabetes. Formation of receptor-independent channels by hIAPP in membrane is regarded as one of the membrane-damaging mechanis...

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Autors principals: Zhao, Jun, Luo, Yin, Jang, Hyunbum, Yu, Xiang, Wei, Guanghong, Nussinov, Ruth, Zheng, Jie
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3455117/
https://ncbi.nlm.nih.gov/pubmed/22935354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2012.08.012
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