Nitroaromatic radiation sensitizers substitute for oxygen in neocarzinostatin-induced DNA damage.
The ability of neocarzinostatin (NCS) chromophore to damage DNA, as manifested by strand breaks and base release, is markedly decreased under anaerobic conditions but can be restored by nitroaromatic radiation sensitizers, which by themselves have no effect. The effectiveness of these compounds is c...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1984
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345497/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6233608/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.11.3312 |
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