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Evidence for the multicentric origin of the sickle cell hemoglobin gene in Africa.

Previous studies of the Hpa I cleavage site-sickle cell hemoglobin gene linkage in various African populations suggested that the sickle gene arose independently more than once. In the present study we have performed restriction endonuclease haplotype analysis for the beta-globin-like gene cluster f...

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Autors principals: Pagnier, J, Mears, J G, Dunda-Belkhodja, O, Schaefer-Rego, K E, Beldjord, C, Nagel, R L, Labie, D
Format: Artigo
Idioma:Inglês
Publicat: 1984
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC345002/
https://ncbi.nlm.nih.gov/pubmed/6584911
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