A gene conversion located 5' to the A gamma gene in linkage disequilibrium with the Bantu haplotype in sickle cell anemia.

Cloning and sequencing of the gamma-globin gene of a sickle cell anemia patient homozygous for the Bantu haplotype has revealed a gene conversion that involves the replacement of an A gamma sequence by a G gamma sequence in the promoter area of the A gamma gene. This event is similar to another gene...

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Publié dans:	J Clin Invest
Auteurs principaux:	Bouhassira, E E, Lachman, H, Krishnamoorthy, R, Labie, D, Nagel, R L
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1989
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303932/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2723072/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114118
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