A novel beta thalassemia gene with a single base mutation in the conserved polypyrimidine sequence at the 3' end of IVS 2.

An adult Algerian patient with homozygous beta thalassemia was found to have a unique beta thalassemia gene. Cloning and sequencing revealed that the only abnormality present in this beta gene is a transversion in the polypyrimidine stretch at the 3' end of the large intervening sequence (IVS 2...

Full description

Saved in:

Bibliographic Details
Main Authors:	Beldjord, C, Lapoumeroulie, C, Pagnier, J, Benabadji, M, Krishnamoorthy, R, Labie, D, Bank, A
Format:	Artigo
Language:	Inglês
Published:	1988
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC336707/ https://ncbi.nlm.nih.gov/pubmed/3387213
Tags:	Add Tag No Tags, Be the first to tag this record!

A novel beta thalassemia gene with a single base mutation in the conserved polypyrimidine sequence at the 3' end of IVS 2.

Similar Items