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A gene conversion located 5' to the A gamma gene in linkage disequilibrium with the Bantu haplotype in sickle cell anemia.

Cloning and sequencing of the gamma-globin gene of a sickle cell anemia patient homozygous for the Bantu haplotype has revealed a gene conversion that involves the replacement of an A gamma sequence by a G gamma sequence in the promoter area of the A gamma gene. This event is similar to another gene...

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Vydáno v:J Clin Invest
Hlavní autoři: Bouhassira, E E, Lachman, H, Krishnamoorthy, R, Labie, D, Nagel, R L
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1989
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303932/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2723072/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114118
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