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Expression of a beta thalassemia gene with abnormal splicing.

Expression of a cloned human beta thalassemia gene with a single base change at position 5 of IVS 1 has been analyzed 48 hours after transfer of the gene into HeLa cells (transient expression). Little or no normal beta globin mRNA accumulates in the presence of the abnormal beta gene in contrast to...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Lapoumeroulie, C, Acuto, S, Rouabhi, F, Labie, D, Krishnamoorthy, R, Bank, A
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 1987
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306353/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3671081/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.20.8195
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