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Expression of a beta thalassemia gene with abnormal splicing.

Expression of a cloned human beta thalassemia gene with a single base change at position 5 of IVS 1 has been analyzed 48 hours after transfer of the gene into HeLa cells (transient expression). Little or no normal beta globin mRNA accumulates in the presence of the abnormal beta gene in contrast to...

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Udgivet i:Nucleic Acids Res
Principais autores: Lapoumeroulie, C, Acuto, S, Rouabhi, F, Labie, D, Krishnamoorthy, R, Bank, A
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1987
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306353/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3671081/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.20.8195
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