Evidence for the multicentric origin of the sickle cell hemoglobin gene in Africa.

Previous studies of the Hpa I cleavage site-sickle cell hemoglobin gene linkage in various African populations suggested that the sickle gene arose independently more than once. In the present study we have performed restriction endonuclease haplotype analysis for the beta-globin-like gene cluster f...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Pagnier, J, Mears, J G, Dunda-Belkhodja, O, Schaefer-Rego, K E, Beldjord, C, Nagel, R L, Labie, D
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1984
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345002/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6584911/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.6.1771
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