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The Role of Amino Acids in Extracellular Loops of the Human P2Y(1) Receptor in Surface Expression and Activation Processes(*)
The P2Y(1) receptor is a membrane-bound G protein-coupled receptor stimulated by adenine nucleotides. Using alanine scanning mutagenesis, the role in receptor activation of charged amino acids (Asp, Glu, Lys, and Arg) and cysteines in the extracellular loops (EL) of the human P2Y(1) receptor has bee...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3449168/ https://ncbi.nlm.nih.gov/pubmed/10329657 |
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