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Association between hTERT activation by HPV E6 proteins and oncogenic risk
Expression of activated telomerase and subversion of the p16/pRb pathway is sufficient and essential for the in vitro immortalization of primary keratinocytes. Most cancers - including cervical carcinoma - over-express hTERT, the catalytic domain of the telomerase complex. Only a limited set of viru...
में बचाया:
| मुख्य लेखकों: | , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3449093/ https://ncbi.nlm.nih.gov/pubmed/22925336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.08.006 |
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