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Structure of the Alk1 extracellular domain and characterization of its BMP binding properties

Bone morphogenetic proteins (BMPs) are secreted signaling proteins – they transduce their signals by by assembling complexes comprised of one of three known type II receptors and one of four known type I receptors. BMP-9 binds and signals through the type I receptor Alk1, but not other Alks, while B...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Mahlawat, Pardeep, Ilangovan, Udayar, Biswas, Tanuka, Sun, LuZhe, Hinck, Andrew P.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2012
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448977/
https://ncbi.nlm.nih.gov/pubmed/22799562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300942x
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