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Structure of the Alk1 extracellular domain and characterization of its BMP binding properties
Bone morphogenetic proteins (BMPs) are secreted signaling proteins – they transduce their signals by by assembling complexes comprised of one of three known type II receptors and one of four known type I receptors. BMP-9 binds and signals through the type I receptor Alk1, but not other Alks, while B...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3448977/ https://ncbi.nlm.nih.gov/pubmed/22799562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300942x |
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