Structure–activity relationships for the binding of polymyxins with human α-1-acid glycoprotein

Here, for the first time, we have characterized binding properties of the polymyxin class of antibiotics for human α-1-acid glycoprotein (AGP) using a combination of biophysical techniques. The binding affinity of colistin, polymyxin B, polymyxin B(3), colistin methansulfonate, and colistin nona-pep...

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Detalhes bibliográficos
Main Authors: Azad, Mohammad A.K., Huang, Johnny X., Cooper, Matthew A., Roberts, Kade D., Thompson, Philip E., Nation, Roger L., Li, Jian, Velkov, Tony
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448962/
https://ncbi.nlm.nih.gov/pubmed/22587817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2012.05.004
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