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β(2) adrenergic receptor-induced conformational changes in the heterotrimeric G protein Gs
G protein-coupled receptors (GPCRs) represent the largest family of membrane receptors(1) that instigate signaling through nucleotide exchange on heterotrimeric G proteins. Nucleotide exchange, or more precisely GDP dissociation from the G protein α-subunit, is the key step toward G protein activati...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3448949/ https://ncbi.nlm.nih.gov/pubmed/21956331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10488 |
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