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Associations between the Expression of Epigenetically Regulated Genes and the Expression of DNMTs and MBDs in Systemic Lupus Erythematosus

OBJECTIVES: We determined the expression of ITGAL, PRF1, KIR2DL4, CD70, and CD40LG in patients with SLE and performed correlations with the global DNA methylation status and the levels of three DNA methylation enzymes and two methyl CpG-binding domain (MBD) proteins. PATIENTS AND METHODS: CD4(+) T c...

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Dettagli Bibliografici
Autori principali: Balada, Eva, Castro-Marrero, Jesús, Felip, Lledó, Ordi-Ros, Josep, Vilardell-Tarrés, Miquel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448686/
https://ncbi.nlm.nih.gov/pubmed/23029299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045897
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