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Associations between the Expression of Epigenetically Regulated Genes and the Expression of DNMTs and MBDs in Systemic Lupus Erythematosus

OBJECTIVES: We determined the expression of ITGAL, PRF1, KIR2DL4, CD70, and CD40LG in patients with SLE and performed correlations with the global DNA methylation status and the levels of three DNA methylation enzymes and two methyl CpG-binding domain (MBD) proteins. PATIENTS AND METHODS: CD4(+) T c...

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Autors principals: Balada, Eva, Castro-Marrero, Jesús, Felip, Lledó, Ordi-Ros, Josep, Vilardell-Tarrés, Miquel
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448686/
https://ncbi.nlm.nih.gov/pubmed/23029299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045897
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