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Associations between the Expression of Epigenetically Regulated Genes and the Expression of DNMTs and MBDs in Systemic Lupus Erythematosus

OBJECTIVES: We determined the expression of ITGAL, PRF1, KIR2DL4, CD70, and CD40LG in patients with SLE and performed correlations with the global DNA methylation status and the levels of three DNA methylation enzymes and two methyl CpG-binding domain (MBD) proteins. PATIENTS AND METHODS: CD4(+) T c...

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Autores principales: Balada, Eva, Castro-Marrero, Jesús, Felip, Lledó, Ordi-Ros, Josep, Vilardell-Tarrés, Miquel
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448686/
https://ncbi.nlm.nih.gov/pubmed/23029299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045897
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