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Transcript levels of DNA methyltransferases DNMT1, DNMT3A and DNMT3B in CD4(+) T cells from patients with systemic lupus erythematosus

Global DNA hypomethylation in CD4(+) T cells has been detected in systemic lupus erythematosus (SLE) and it seems to be linked to its pathogenesis. We investigated the relationship between overall DNA methylation and the expression of three DNA (cytosine-5) methyltransferases involved in the DNA met...

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Detalhes bibliográficos
Main Authors: Balada, Eva, Ordi-Ros, Josep, Serrano-Acedo, Silvia, Martinez-Lostao, Luis, Rosa-Leyva, Maria, Vilardell-Tarrés, Miquel
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440828/
https://ncbi.nlm.nih.gov/pubmed/18194272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02771.x
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