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Associations between the Expression of Epigenetically Regulated Genes and the Expression of DNMTs and MBDs in Systemic Lupus Erythematosus

OBJECTIVES: We determined the expression of ITGAL, PRF1, KIR2DL4, CD70, and CD40LG in patients with SLE and performed correlations with the global DNA methylation status and the levels of three DNA methylation enzymes and two methyl CpG-binding domain (MBD) proteins. PATIENTS AND METHODS: CD4(+) T c...

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Detalhes bibliográficos
Main Authors: Balada, Eva, Castro-Marrero, Jesús, Felip, Lledó, Ordi-Ros, Josep, Vilardell-Tarrés, Miquel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448686/
https://ncbi.nlm.nih.gov/pubmed/23029299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045897
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