Inhibition of stromal CXCR4 impairs development of lung metastases

Compelling evidence has emerged in recent years indicating that stromal cells play a critical role in disease progression. CXCR4 is a G-protein-coupled receptor with a major role in lymphocyte homing. Its ligand, CXCL12, is a highly efficient chemotactic factor for T cells, monocytes, pre-B cells, d...

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Détails bibliographiques
Auteurs principaux: D’Alterio, Crescenzo, Barbieri, Antonio, Portella, Luigi, Palma, Giuseppe, Polimeno, Marianeve, Riccio, Anna, Ieranò, Caterina, Franco, Renato, Scognamiglio, Giosuè, Bryce, Jane, Luciano, Antonio, Rea, Domenica, Arra, Claudio, Scala, Stefania
Format: Artigo
Langue:Inglês
Publié: Springer-Verlag 2012
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448054/
https://ncbi.nlm.nih.gov/pubmed/22399057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-012-1223-7
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