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Inhibition of stromal CXCR4 impairs development of lung metastases
Compelling evidence has emerged in recent years indicating that stromal cells play a critical role in disease progression. CXCR4 is a G-protein-coupled receptor with a major role in lymphocyte homing. Its ligand, CXCL12, is a highly efficient chemotactic factor for T cells, monocytes, pre-B cells, d...
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| Auteurs principaux: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer-Verlag
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3448054/ https://ncbi.nlm.nih.gov/pubmed/22399057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-012-1223-7 |
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