A novel CXCR4-targeted near-infrared (NIR) fluorescent probe (Peptide R-NIR750) specifically detects CXCR4 expressing tumors

C-X-C chemokine receptor 4 (CXCR4) is over-expressed in multiple human cancers and correlates with tumor aggressiveness, poor prognosis and increased risk for distant metastases. Imaging agents for CXCR4 are thus highly desirable. We developed a novel CXCR4-targeted near-infrared (NIR) fluorescent p...

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Udgivet i:Sci Rep
Main Authors: Santagata, Sara, Portella, Luigi, Napolitano, Maria, Greco, Adelaide, D’Alterio, Crescenzo, Barone, Maria Vittoria, Luciano, Antonio, Gramanzini, Matteo, Auletta, Luigi, Arra, Claudio, Zannetti, Antonella, Scala, Stefania
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451476/
https://ncbi.nlm.nih.gov/pubmed/28566721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02818-6
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