New CXCR4 Antagonist Peptide R (Pep R) Improves Standard Therapy in Colorectal Cancer

The chemokine receptor CXCR4 is overexpressed and functional in colorectal cancer. To investigate the role of CXCR4 antagonism in potentiating colon cancer standard therapy, the new peptide CXCR4 antagonist Peptide R (Pep R) was employed. Human colon cancer HCT116 xenograft-bearing mice were treated...

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Vydáno v:Cancers (Basel)
Hlavní autoři: D’Alterio, Crescenzo, Zannetti, Antonella, Trotta, Anna Maria, Ieranò, Caterina, Napolitano, Maria, Rea, Giuseppina, Greco, Adelaide, Maiolino, Piera, Albanese, Sandra, Scognamiglio, Giosuè, Tatangelo, Fabiana, Tafuto, Salvatore, Portella, Luigi, Santagata, Sara, Nasti, Guglielmo, Ottaiano, Alessandro, Pacelli, Roberto, Delrio, Paolo, Botti, Gerardo, Scala, Stefania
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409147/
https://ncbi.nlm.nih.gov/pubmed/32708431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12071952
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