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Crystal Structure of the Human NKX2.5 Homeodomain in Complex with DNA Target

[Image: see text] NKX2.5 is a homeodomain containing transcription factor regulating cardiac formation and function, and its mutations are linked to congenital heart disease. Here we provide the first report of the crystal structure of the NKX2.5 homeodomain in complex with double-stranded DNA of it...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pradhan, Lagnajeet, Genis, Caroli, Scone, Peyton, Weinberg, Ellen O., Kasahara, Hideko, Nam, Hyun-Joo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448007/
https://ncbi.nlm.nih.gov/pubmed/22849347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300849c
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