Relacin, a Novel Antibacterial Agent Targeting the Stringent Response

Finding bacterial cellular targets for developing novel antibiotics has become a major challenge in fighting resistant pathogenic bacteria. We present a novel compound, Relacin, designed to inhibit (p)ppGpp production by the ubiquitous bacterial enzyme RelA that triggers the Stringent Response. Rela...

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Detalles Bibliográficos
Main Authors: Wexselblatt, Ezequiel, Oppenheimer-Shaanan, Yaara, Kaspy, Ilana, London, Nir, Schueler-Furman, Ora, Yavin, Eylon, Glaser, Gad, Katzhendler, Joshua, Ben-Yehuda, Sigal
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447753/
https://ncbi.nlm.nih.gov/pubmed/23028324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002925
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