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Can Self-Inhibitory Peptides be Derived from the Interfaces of Globular Protein-Protein Interactions?

In this study, we assess on a large scale the possibility of deriving self-inhibitory peptides from protein domains with globular architectures. Such inhibitory peptides would inhibit interactions of their origin domain by mimicking its mode of binding to cognate partners, and could serve as promisi...

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Detalles Bibliográficos
Main Authors: London, Nir, Raveh, Barak, Movshovitz-Attias, Dana, Schueler-Furman, Ora
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952690/
https://ncbi.nlm.nih.gov/pubmed/20607702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22785
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