c-di-AMP reports DNA integrity during sporulation in Bacillus subtilis

The bacterium Bacillus subtilis produces the DNA integrity scanning protein (DisA), a checkpoint protein that delays sporulation in response to DNA damage. DisA scans the chromosome and pauses at sites of DNA lesions. Structural analysis showed that DisA synthesizes the small molecule cyclic diadeno...

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Detalhes bibliográficos
Main Authors: Oppenheimer-Shaanan, Yaara, Wexselblatt, Ezequiel, Katzhendler, Jehoshua, Yavin, Eylon, Ben-Yehuda, Sigal
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128283/
https://ncbi.nlm.nih.gov/pubmed/21566650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.77
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