Identification and Characterization of Potential Impurities in Raloxifene Hydrochloride

During the synthesis of the bulk drug Raloxifene hydrochloride, eight impurities were observed, four of which were found to be new. All of the impurities were detected using the gradient high performance liquid chromatographic (HPLC) method, whose area percentages ranged from 0.05 to 0.1%. LCMS was...

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Detalhes bibliográficos
Main Authors: Reddy, Reguri Buchi, Goud, Thirumani Venkateshwar, Nagamani, Nagabushanam, Kumar, Nutakki Pavan, Alagudurai, Anandan, Murugan, Raman, Parthasarathy, Kannabiran, Karthikeyan, Vinayagam, Balaji, Perumal
Formato: Artigo
Idioma:Inglês
Publicado em: Österreichische Apotheker-Verlagsgesellschaft 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447609/
https://ncbi.nlm.nih.gov/pubmed/23008809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1204-13
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