Identification and Characterization of Potential Impurities in Raloxifene Hydrochloride

During the synthesis of the bulk drug Raloxifene hydrochloride, eight impurities were observed, four of which were found to be new. All of the impurities were detected using the gradient high performance liquid chromatographic (HPLC) method, whose area percentages ranged from 0.05 to 0.1%. LCMS was...

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Hauptverfasser: Reddy, Reguri Buchi, Goud, Thirumani Venkateshwar, Nagamani, Nagabushanam, Kumar, Nutakki Pavan, Alagudurai, Anandan, Murugan, Raman, Parthasarathy, Kannabiran, Karthikeyan, Vinayagam, Balaji, Perumal
Format: Artigo
Sprache:Inglês
Veröffentlicht: Österreichische Apotheker-Verlagsgesellschaft 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447609/
https://ncbi.nlm.nih.gov/pubmed/23008809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1204-13
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