Identification and Characterization of Potential Impurities in Raloxifene Hydrochloride

During the synthesis of the bulk drug Raloxifene hydrochloride, eight impurities were observed, four of which were found to be new. All of the impurities were detected using the gradient high performance liquid chromatographic (HPLC) method, whose area percentages ranged from 0.05 to 0.1%. LCMS was...

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Главные авторы: Reddy, Reguri Buchi, Goud, Thirumani Venkateshwar, Nagamani, Nagabushanam, Kumar, Nutakki Pavan, Alagudurai, Anandan, Murugan, Raman, Parthasarathy, Kannabiran, Karthikeyan, Vinayagam, Balaji, Perumal
Формат: Artigo
Язык:Inglês
Опубликовано: Österreichische Apotheker-Verlagsgesellschaft 2012
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447609/
https://ncbi.nlm.nih.gov/pubmed/23008809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1204-13
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