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Detection, Isolation and Characterization of Principal Synthetic Route Indicative Impurities in Verapamil Hydrochloride

Two unknown impurities were detected in verapamil hydrochloride bulk drug using isocratic reversed-phase high performance liquid chromatography (HPLC). These impurities were isolated by preparative HPLC. Spectral data for the isolated impurities were collected. Based on the spectral data derived fro...

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Detalhes bibliográficos
Main Authors: Srinivasan, Viswanathan, Sivaramakrishnan, Hariharan, Karthikeyan, Balakrishnan
Formato: Artigo
Idioma:Inglês
Publicado em: Österreichische Apotheker-Verlagsgesellschaft 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163365/
https://ncbi.nlm.nih.gov/pubmed/21886903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1101-19
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