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Study on Isomeric Impurities in Cefotiam Hydrochloride
In this study, two isomeric impurities were identified in cefotiam hydrochloride injection preparation and were characterized. Column-switching HPLC-MS and NMR techniques were used to identify the impurity 1 as the Δ3(4) isomers of cefotiam. Using software-based calculations, it was predicted that n...
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| Vydáno v: | Front Chem |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Frontiers Media S.A.
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7873999/ https://ncbi.nlm.nih.gov/pubmed/33585401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2020.619307 |
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