p53 and miRNA-34 are Suppressors of Canonical Wnt Signaling

Although loss of p53 function and activation of canonical Wnt signaling cascades are frequently coupled in cancer, the links between these two pathways remain unclear. We report here that p53 transactivates miRNA-34 (miR-34), which suppresses the transcriptional activity of β-catenin-T-cell factor/l...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Kim, Nam Hee, Kim, Hyun Sil, Kim, Nam-Gyun, Lee, Inhan, Choi, Hyung-Seok, Li, Xiao-Yan, Kang, Shi Eun, Cha, So Young, Ryu, Joo Kyung, Na, Jung Min, Park, Changbum, Kim, Kunhong, Lee, Sanghyuk, Gumbiner, Barry M., Yook, Jong In, Weiss, Stephen J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447368/
https://ncbi.nlm.nih.gov/pubmed/22045851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2001744
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky