Limited effect of anti-rheumatic treatment on 15-prostaglandin dehydrogenase in rheumatoid arthritis synovial tissue

INTRODUCTION: Rheumatoid arthritis (RA) is a chronic inflammatory disease in which prostaglandin E(2 )(PGE(2)) displays an important pathogenic role. The enzymes involved in its synthesis are highly expressed in the inflamed synovium, while little is known about 15- prostaglandin dehydrogenase (15-P...

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Bibliografske podrobnosti
Main Authors: Gheorghe, Karina Roxana, Sadique, Syed, Leclerc, Patrick, Idborg, Helena, Wobst, Ivonne, Catrina, Anca Irinel, Jakobsson, Per-Johan, Korotkova, Marina
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446502/
https://ncbi.nlm.nih.gov/pubmed/22616846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3851
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