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Synovial membrane immunohistology in early-untreated rheumatoid arthritis reveals high expression of catabolic bone markers that is modulated by methotrexate

INTRODUCTION: We aimed to investigate the expression and therapeutic modulation of the receptor activator of the NF-κB ligand (RANKL) system in early-untreated rheumatoid arthritis (RA). METHODS: In this study, 15 patients with newly diagnosed RA (median symptom duration 7 months) were started on me...

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Detalhes bibliográficos
Main Authors: Revu, Shankar, Neregård, Petra, af Klint, Erik, Korotkova, Marina, Catrina, Anca Irinel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978873/
https://ncbi.nlm.nih.gov/pubmed/24295447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4398
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