Expression of 5-lipoxygenase and 15-lipoxygenase in rheumatoid arthritis synovium and effects of intraarticular glucocorticoids

INTRODUCTION: It was previously shown that lipoxygenase (LO) pathways are important in the rheumatoid arthritis (RA) inflammatory process and that synovial fluid from RA patients contains high amounts of leukotrienes. We therefore aimed to investigate the 5-LO and 15-LO-1 expression pattern in RA an...

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Autores principales: Gheorghe, Karina Roxana, Korotkova, Marina, Catrina, Anca Irinel, Backman, Linda, af Klint, Erik, Claesson, Hans-Erik, Rådmark, Olof, Jakobsson, Per-Johan
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714134/
https://ncbi.nlm.nih.gov/pubmed/19497113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2717
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