Expression of 5-lipoxygenase and 15-lipoxygenase in rheumatoid arthritis synovium and effects of intraarticular glucocorticoids

INTRODUCTION: It was previously shown that lipoxygenase (LO) pathways are important in the rheumatoid arthritis (RA) inflammatory process and that synovial fluid from RA patients contains high amounts of leukotrienes. We therefore aimed to investigate the 5-LO and 15-LO-1 expression pattern in RA an...

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Autori principali: Gheorghe, Karina Roxana, Korotkova, Marina, Catrina, Anca Irinel, Backman, Linda, af Klint, Erik, Claesson, Hans-Erik, Rådmark, Olof, Jakobsson, Per-Johan
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714134/
https://ncbi.nlm.nih.gov/pubmed/19497113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2717
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