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Prostaglandin E(2) Synthesizing Enzymes in Rheumatoid Arthritis B Cells and the Effects of B Cell Depleting Therapy on Enzyme Expression

INTRODUCTION: B cells may play an important role in promoting immune activation in the rheumatoid synovium and can produce prostaglandin E(2) (PGE(2)) when activated. In its turn, PGE(2) formed by cyclooxygenase (COX) and microsomal prostaglandin E(2) synthase 1 (MPGES1) contributes to the rheumatoi...

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書誌詳細
主要な著者: Gheorghe, Karina Roxana, Thurlings, Rogier M., Westman, Marie, Boumans, Maartje J., Malmström, Vivianne, Trollmo, Christina, Korotkova, Marina, Jakobsson, Per-Johan, Tak, Paul-Peter
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029314/
https://ncbi.nlm.nih.gov/pubmed/21298002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016378
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