Prostaglandin E(2) Synthesizing Enzymes in Rheumatoid Arthritis B Cells and the Effects of B Cell Depleting Therapy on Enzyme Expression

INTRODUCTION: B cells may play an important role in promoting immune activation in the rheumatoid synovium and can produce prostaglandin E(2) (PGE(2)) when activated. In its turn, PGE(2) formed by cyclooxygenase (COX) and microsomal prostaglandin E(2) synthase 1 (MPGES1) contributes to the rheumatoi...

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Библиографические подробности
Главные авторы: Gheorghe, Karina Roxana, Thurlings, Rogier M., Westman, Marie, Boumans, Maartje J., Malmström, Vivianne, Trollmo, Christina, Korotkova, Marina, Jakobsson, Per-Johan, Tak, Paul-Peter
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029314/
https://ncbi.nlm.nih.gov/pubmed/21298002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016378
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