The anti-CD74 humanized monoclonal antibody, milatuzumab, which targets the invariant chain of MHC II complexes, alters B-cell proliferation, migration, and adhesion molecule expression

INTRODUCTION: Targeting CD74 as the invariant chain of major histocompatibility complexes (MHC) became possible by the availability of a specific humanized monoclonal antibody, milatuzumab, which is under investigation in patients with hematological neoplasms. CD74 has been reported to regulate chem...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Frölich, Daniela, Blaβfeld, Daniela, Reiter, Karin, Giesecke, Claudia, Daridon, Capucine, Mei, Henrik E, Burmester, Gerd R, Goldenberg, David M, Salama, Abdulagabar, Dörner, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446420/
https://ncbi.nlm.nih.gov/pubmed/22404985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3767
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge